D# Mixolydian is a major-sounding scale with a little grit in it. It's bright and upbeat like a major scale, but one note gives it a bluesy, rock-and-roll swagger. If you've ever wanted your solos to sound less like a nursery rhyme and more like a bar band on a Saturday night, this is one of the first sounds worth getting under your fingers. Let's look at the notes, why they're spelled the way they are, the chords you get from them and where to find everything on the neck.
Here are the seven notes:
D#, E#, F##, G#, A#, B#, C#
Your eyes probably stopped at E#, B# and that odd-looking F##. Don't worry, nothing is broken, and you haven't missed a lesson. Here's what's going on.
A sharp (#) raises a note by one half step. A half step is the distance of one fret on the guitar. So E# is simply one fret above E, the same fret you'd normally call F. B# is one fret above B, the same fret you'd usually call C. A double sharp (##) raises a note by two frets, so F## is two frets above F, landing on the same fret as G.
Why not just call them F, C and G? Because of a simple rule: a scale like this uses every letter name once, in order. D, E, F, G, A, B, C. Keeping that rule makes the theory consistent, even if it looks strange on paper.
D# Mixolydian is what musicians call a theoretical key. It needs double sharps to be written correctly, which makes it awkward to read. In the real world, most players and songbooks write the same sound as Eb Mixolydian, which uses a much tidier key signature of 4 flats. It sounds exactly the same. Same frets, same sound, different names. If a bandmate says Eb Mixolydian, you'll be playing the very same notes.
Every scale is a pattern of steps. A whole step (W) is two frets; a half step (H) is one fret. Mixolydian follows this pattern:
W - W - H - W - W - H - W
Start on D# and walk it through:
You can try this on a single string. Put your finger on the 6th fret of the A string (that's D#) and move up two frets, two frets, one fret, two, two, one, two. You'll land on D# again at the 18th fret, one octave higher (the same note, just higher in pitch).
The formula for Mixolydian is 1, 2, 3, 4, 5, 6, b7. That's almost a regular major scale. The only difference is the seventh note, which is lowered by a half step. That's the flat 7th (b7).
In this key, the flat 7th is C#. That one note is the whole personality of the scale. A normal major scale has a seventh note that pulls hard back up to the root, like a question waiting for an answer. The flat 7th is more relaxed. It sits a whole step (two frets) below the root and gives you that laid-back, bluesy, classic-rock feel.
When you play the scale, lean on C# and listen. It should sound a little cheeky against a D# chord, not wrong, just full of attitude. Then resolve to D# and feel it settle.
Here's another way to see it: D# Mixolydian uses the same notes as G# major (G#, A#, B#, C#, D#, E#, F##). The difference is where home is. In Mixolydian, you start and end on D#, so your ear hears D# as the centre.
Stack notes from the scale in thirds (every other note) and you get a family of chords. Here they are, as simple three-note chords (triads) and as four-note seventh chords:
Notice that the home chord is D#7, not a plain major seven chord. That's the flat 7th at work. And the bVII chord, C#, is the signature Mixolydian move. Going from C# to D# is a sound you've heard in countless rock songs.
Try this classic loop, one bar each:
D# - C# - G# - D#
That's I - bVII - IV - I. Record it, or loop it slowly, then improvise with the scale over the top. When the C# chord comes round, the C# note in your melody will sound right at home. When you're back on D#, finish your phrases on D# and hear how they land.
On a standard-tuned six-string guitar, your D# root notes are easy to find:
The 6th fret on the A string is a great home base. It's comfortable, it's in the middle of the neck, and you can play the scale around it without stretching. The 11th fret on the low E string gives you a second position just higher up. Learn to jump between these two spots and you'll always know where home is.
Spend five minutes today just playing D# to C# and back, over and over, on the A string at frets 6 and 4. Get that flat 7th sound in your ear. Then loop the D# - C# - G# progression and make up short, simple phrases, two or three notes at a time. Don't chase speed. Chase the feeling. Once that bluesy major sound clicks, you'll start hearing it everywhere.
For the bigger picture, read The Mixolydian Mode.